FH Protein (AA 44-510)

Produktnummer ABIN666730

Recombinant FH-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für FH Protein (AA 44-510) (ABIN666730)

Target: FH (Fumarate Hydratase (FH))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 95 % by SDS - PAGE

Produktdetails

Proteineigenschaft: AA 44-510

Produktmerkmale: Fumarase, 44-510aa, Human, Recombinant, E.coli

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH 8.0)

Lagerung: 4 °C

Antigendetails

Target: FH (Fumarate Hydratase (FH))

Andere Bezeichnung: Fumarase

Hintergrund: Fumarase (Fumarate hytdratase) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid (TCA), or Krebs cycle. This enzyme exists in both a cytosolic form and an N-terminal extended mitochondrial form. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension is the same form as in the cytoplasm. Fumarase deficiency can lead to progressive encephalopathy, cerebral atrophy and developmental delay and this enzyme also is thought to act as a tumor suppressor. Recombinant Fumarase was expressed in E.coli and was purified by conventional chromatography techniques. Synonyms: FH, HLRCC, LRCC, MCL, MCUL1 , Fumarate hydratase Fumarase, Fumarate hydratase mitochondrial, MCUL 1, Multiple hereditary cutaneous leiomyomata. NCBI no.: NP_000134

Molekulargewicht: 50.2kDa (467aa), confirmed by MALDI-TOF.