VSNL1 Protein (AA 1-191)

Produktnummer ABIN666662

Produktdetails

Target: VSNL1 (Visinin-Like 1 (VSNL1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-191

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Produktmerkmale: Visinin-like protein-1, 1-191 aa, Human, Recombinant, E.coli

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 1mM DTT,10% glycerol

Lagerung: 4 °C

Antigendetails

Target: VSNL1 (Visinin-Like 1 (VSNL1))

Andere Bezeichnung: Visinin-like protein-1 (VSNL1 Produkte)

Synonyme: HLP3 Protein, HPCAL3 Protein, HUVISL1 Protein, VILIP Protein, VILIP-1 Protein, Nvp1 Protein, Ratnvp1 Protein, Vnsl1 Protein, MGC132057 Protein, MGC146004 Protein, VSNL1 Protein, si:dkey-15f12.11 Protein, si:dkey-30j22.11 Protein, zgc:103644 Protein, hlp3 Protein, vilip Protein, hpcal3 Protein, huvisl1 Protein, vilip-1 Protein, visinin like 1 Protein, visinin-like 1 Protein, visinin like 1 S homeolog Protein, visinin-like 1a Protein, visinin like 1 L homeolog Protein, VSNL1 Protein, Vsnl1 Protein, vsnl1.S Protein, vsnl1 Protein, vsnl1a Protein, vsnl1.L Protein

Hintergrund: Visinin-like protein-1, also known as VILIP-1, belongs to a family of neuronal calcium sensor proteins. VILIP-1 is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Also, it is expressed in pancreatic beta-cells. VILIP-1 elevation enhances insulin secretion in cAMP-associated manner. Down-regulation of VILIP-1 decreased cAMP accumulation but increased insulin gene transcription. Recombinant human Visinin-like protein-1 was expressed in E.coli and purified by using conventional chromatography. Synonyms: VILIP, VILIP-1, VLP-1, HLP3, VSNL1 , Hippocalcin like protein 3, HLP 3, HPCAL 3, HPCAL3, HUVISL1, Neurocalcin alpha, NVL 1, NVL1, VILIP, Visinin.Visinin like 1, Visinin like protein 1.VISL 1. NCBI no.: NP_003376

Molekulargewicht: 22.1 kDa (191aa), confirmed by MALDI-TOF.