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CD52 Protein (CD52) (AA 25-36) (hIgG-His-tag)

Dieses Recombinant CD52-Protein wird in Baculovirus infected Insect Cells exprimiert.
Produktnummer ABIN6388178

Kurzübersicht für CD52 Protein (CD52) (AA 25-36) (hIgG-His-tag) (ABIN6388178)

Target

Alle CD52 Proteine anzeigen
CD52

Protein-Typ

Recombinant

Spezies

  • 12
  • 1
Human

Quelle

  • 8
  • 3
  • 1
  • 1
Baculovirus infected Insect Cells

Applikation

SDS-PAGE (SDS)

Reinheit

> 95% by SDS-PAGE
  • Proteineigenschaft

    AA 25-36

    Aufreinigungstag / Konjugat

    Dieses CD52 Protein ist gelabelt mit hIgG-His-tag.

    Sequenz

    GQNDTSQTSS PSLEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H

    Endotoxin-Niveau

    < 1 EU per 1ug of protein (determined by LAL method)
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  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.5 mg/mL

    Buffer

    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

    Lagerung

    4 °C,-20 °C,-80 °C

    Informationen zur Lagerung

    Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
  • Target

    CD52

    Andere Bezeichnung

    CD52

    Hintergrund

    CD52, also known as CAMPATH-1 antigen, is a small glycosylphosphatidylinositol (GPI) anchored glycoprotein that is tethered to the cell surface with a GPI linkage. This protein can be targeted to induce immune suppression by complement-meditated cell lysis. CD52 is expressed on lymphocytes, monocytes, monocytes-derived dendritic cells, eosinophils, and neutrophils, but not on the stem cells from which these lymphocytes were derived. Also, it is an important target for therapeutic interventions aimed at leukocyte depletion in hematological malignancies and post-transplant immunosuppression. Recombinant human CD52, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

    Molekulargewicht

    28.2 kDa (251aa)

    NCBI Accession

    NP_001794

    UniProt

    P31358
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