TARDBP Protein (AA 1-414)
Kurzübersicht für TARDBP Protein (AA 1-414) (ABIN7281189)
Target
Alle TARDBP Proteine anzeigenProtein-Typ
Spezies
Quelle
Applikation
Reinheit
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Proteineigenschaft
- AA 1-414
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Sequenz
- MSEYIRVTED ENDEPIEIPS EDDGTVLLST VTAQFPGACG LRYRNPVSQC MRGVRLVEGI LHAPDAGWGN LVYVVNYPKD NKRKMDETDA SSAVKVKRAV QKTSDLIVLG LPWKTTEQDL KEYFSTFGEV LMVQVKKDLK TGHSKGFGFV RFTEYETQVK VMSQRHMIDG RWCDCKLPNS KQSQDEPLRS RKVFVGRCTE DMTEDELREF FSQYGDVMDV FIPKPFRAFA FVTFADDQIA QSLCGEDLII KGISVHISNA EPKHNSNRQL ERSGRFGGNP GGFGNQGGFG NSRGGGAGLG NNQGSNMGGG MNFGAFSINP AMMAAAQAAL QSSWGMMGML ASQQNQSGPS GNNQNQGNMQ REPNQAFGSG NNSYSGSNSG AAIGWGSASN AGSGSGFNGG FGSSMDSKSS GWGM
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Möchten Sie weitere Optionen für dieses Protein ?
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TAR DNA Binding Protein (TARDBP) (AA 1-414) protein (His tag)
custom-made TARDBP Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
TAR DNA Binding Protein (TARDBP) (AA 1-414) protein (His tag)custom-made TARDBP Spezies: Maus Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
TAR DNA Binding Protein (TARDBP) protein (Myc-DYKDDDDK Tag)TARDBP Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
TAR DNA Binding Protein (TARDBP) (AA 1-260) protein (His tag)TARDBP Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
TAR DNA Binding Protein (TARDBP) (AA 8-192) protein (His-IF2DI Tag)TARDBP Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA
TAR DNA Binding Protein (TARDBP) (AA 1-414) protein (GST tag)TARDBP Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
TAR DNA Binding Protein (TARDBP) (AA 1-260) protein (GST tag)TARDBP Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
TAR DNA Binding Protein (TARDBP) (AA 1-414) protein (His tag)TARDBP Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- Liquid. In 20 mM Tris-HCl( pH 8.0) containing 0.1M NaCl, 1 mM DTT, 1 mM EDTA, 10 % glycerol
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Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- TARDBP (TAR DNA Binding Protein (TARDBP))
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Andere Bezeichnung
- TDP-43/TARDBP
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Hintergrund
- TARDBP, as known as TAR DNA binding protein 43, was originally identified as a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. It has also been identified in individuals diagnosed with chronic traumatic encephalopathy, a condition that often mimics ALS and that has been associated with athletes who have experienced multiple concussions and other types of head injury. It has been shown to bind both DNA and RNA and have multiple functions in transcriptional repression, pre-mRNA splicing and translational regulation. Recombinant human TARDBP protein was expressed in E. coli and purified by using conventional chromatography.
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Molekulargewicht
- 44.7 kDa (414aa)
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NCBI Accession
- NP_031401
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UniProt
- Q13148
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Pathways
- Positive Regulation of Peptide Hormone Secretion
Target
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