PDGF-AA Homodimer Protein

Produktnummer ABIN624786

Dieses Recombinant PDGF-AA Homodimer-Protein wird in not_set exprimiert.

Kurzübersicht für PDGF-AA Homodimer Protein (ABIN624786)

Target: PDGF-AA Homodimer

Protein-Typ: Recombinant

Spezies: Human

Wirt: Bitte anfragen

Reinheit: > 97.0 % as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

Produktdetails

Sequenz: The sequence of the first five N-terminal amino acids was determined and was found to be Ser-Ile-Glu-Glu-Ala.

Produktmerkmale: Recombinant Human Platelet Derived Growth Factor-AA

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: The protein was lyophilized with no additives.It is recommended to reconstitute the lyophilized Platelet-derived Growth Factor-AA in sterile 18M -cm H 2 O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Lagerung: -20 °C

Antigendetails

Target: PDGF-AA Homodimer

Andere Bezeichnung: Platelet-Derived Growth Factor AA

Hintergrund: Platelet-Derived Growth Factor AA Human Recombinant is a homodimeric, non-glycosylated, polypeptide chain containing 2 x 125 amino acids and having a total molecular mass of 28511 Dalton. PDGF-AA is purified by proprietary chromatographic techniques. Introduction: PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGF is stored in platelet alpha-granules and released upon platelet activation. The PDGF is involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGF have been identified and named PDGFR-alpha and PDGFR-beta. PDGFR-alpha is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-beta interacts with only PDGF-BB and PDGF-AB. Synonyms: Glioma-derived growth factor, GDGF, Osteosarcoma-derived Growth Factor, ODGF, PDGF-AA, PDGF-1.