Granulin Protein (GRN) (DYKDDDDK Tag)

Produktnummer ABIN622274

Dieses Recombinant Granulin-Protein wird in exprimiert.

Kurzübersicht für Granulin Protein (GRN) (DYKDDDDK Tag) (ABIN622274)

Target: Granulin (GRN)

Protein-Typ: Recombinant

Spezies: Human

Wirt: Bitte anfragen

Reinheit: > 90.0 % as determined by: a) Analysis by RP-HPLC. b) Analysis by SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses Granulin Protein ist gelabelt mit DYKDDDDK Tag.

Produktmerkmale: Recombinant Human Progranulin

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: The protein solution contains 1x PBS.

Lagerung: -20 °C

Antigendetails

Target: Granulin (GRN)

Andere Bezeichnung: Progranulin

Substanzklasse: Viral Protein

Hintergrund: Progranulin Human Recombinant fused to DYKDDDDK at C-terminus produced in HEK is a single, glycosylated, polypeptide chain containing 593 AA and having a molecular mass of 88 kDa. The Progranulin is purified by standard chromatographic techniques. Introduction: A 88 kDa progranulin, also called proepithelin and PC cell-derived growth factor, is a single precursor protein of granulins which are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. Granulins are a variety of active, 6 kDa peptides and named granulin A (epithelin 1), granulin B (epithelin 2), granulin C, etc. Both the peptides and intact progranulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. Synonyms: GRN, PGRN, granulin, Acrogranin, propithelin, PC cell derived growth Factor, GEP, GP88, PEPI, PCDGF.