Aprotinin Protein (Aprotinin)

Produktnummer ABIN620215

Dieses Native Aprotinin-Protein wird in Cow exprimiert.

Kurzübersicht für Aprotinin Protein (Aprotinin) (ABIN620215)

Target: Aprotinin

Protein-Typ: Native

Spezies: Rind (Kuh)

Quelle: Cow

Reinheit: > 98.0 % as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

Produktdetails

Produktmerkmale: Native Bovine Aprotinin

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: The protein (1 mg/ml) was lyophilized with no additives.It is recommended to reconstitute the lyophilized Aprotinin in sterile 18M omega cm H 2 O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.

Lagerung: -20 °C

Antigendetails

Target: Aprotinin

Andere Bezeichnung: Aprotinin

Hintergrund: Aprotinin is a natural proteinase inhibitor polypeptide consisting of fifty-eight amino acids {C 284 H 432 N 84 O 79 S 7 } arranged in a single polypeptide chain, cross-linked by three disulfide bridges and having a molecular mass of 6512. Introduction: Aprotinin inhibits the activity of several proteolytic enzymes such as chymotrypsin, kallikrein, plasmin and trypsin. Aprotinin is present in blood and in most tissues, with a high concentration in lung. Aprotinin inhibits pro-inflammatory cytokine release and maintains glycoprotein homeostasis. In platelets, aprotinin reduces glycoprotein loss (e.g., GpIb, GpIIb/IIIa), while in granulocytes it prevents the expression of pro-inflammatory adhesive glycoproteins (e.g., CD11b). Synonyms: Pancreatic trypsin inhibitor, Basic protease inhibitor, BPI, BPTI, Aprotinin, AP.