TXN Protein (AA 2-105, full length) (GST tag)

Produktnummer ABIN7479607

Dieses Recombinant TXN-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für TXN Protein (AA 2-105, full length) (GST tag) (ABIN7479607)

Target: TXN (Thioredoxin (TXN))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS), Western Blotting (WB), ELISA

Reinheit: 95 %

Produktdetails

Proteineigenschaft: AA 2-105, full length

Aufreinigungstag / Konjugat: Dieses TXN Protein ist gelabelt mit GST tag.

Sequenz: VKQIESKTAF QEALDAAGDK LVVVDFSATW CGPCKMIKPF FHSLSEKYSN VIFLEVDVDD CQDVASECEV KCMPTFQFFK KGQKVGEFSG ANKEKLEATI NELV

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS buffer, 20mM GSH

Lagerung: 4 °C

Antigendetails

Target: TXN (Thioredoxin (TXN))

Andere Bezeichnung: Thioredoxin

Hintergrund: Background: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. Ref.16 Ref.18 Ref.19 Ref.21 Ref.24 ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55). Synonyms: Short name=Trx Alternative name(s): ATL-derived factor Short name=ADF Surface-associated sulphydryl protein Short name=SASP.

Molekulargewicht: 39 kD

NCBI Accession: NM_003329

UniProt: P10599

Pathways: Carbohydrate Homeostasis, Cell RedoxHomeostasis