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CD33 Protein (CD33) (AA 18-259) (hIgG-His-tag)

CD33 Spezies: Human Wirt: Baculovirus infected Insect Cells Recombinant > 90 % by SDS - PAGE SDS
Produktnummer ABIN5855022
  • Target Alle CD33 Proteine anzeigen
    CD33
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 18-259
    Spezies
    • 35
    • 7
    • 1
    • 1
    Human
    Quelle
    • 30
    • 6
    • 3
    • 3
    • 2
    Baculovirus infected Insect Cells
    Aufreinigungstag / Konjugat
    Dieses CD33 Protein ist gelabelt mit hIgG-His-tag.
    Applikation
    SDS-PAGE (SDS)
    Sequenz
    ADLDPNFWLQ VQESVTVQEG LCVLVPCTFF HPIPYYDKNS PVHGYWFREG AIISGDSPVA TNKLDQEVQE ETQGRFRLLG DPSRNNCSLS IVDARRRDNG SYFFRMERGS TKYSYKSPQL SVHVTDLTHR PKILIPGTLE PGHSKNLTCS VSWACEQGTP PIFSWLSAAP TSLGPRTTHS SVLIITPRPQ DHGTNLTCQV KFAGAGVTTE RTIQLNVTYV PQNPTTGIFP GDGSGKQETR AGVVHLEPKS CDKTHTCPPC PAPELLGGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVKFNWYV DGVEVHNAKT KPREEQYNST YRVVSVLTVL HQDWLNGKEY KCKVSNKALP APIEKTISKA KGQPREPQVY TLPPSRDELT KNQVSLTCLV KGFYPSDIAV EWESNGQPEN NYKTTPPVLD SDGSFFLYSK LTVDKSRWQQ GNVFSCSVMH EALHNHYTQK SLSLSPGKHH HHHH
    Reinheit
    > 90 % by SDS - PAGE
    Endotoxin-Niveau
    < 1.0 EU per 1ug of protein (determined by LAL method)
    Top Product
    Discover our top product CD33 Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.
    Lagerung
    4 °C,-20 °C,-80 °C
    Informationen zur Lagerung
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    CD33
    Andere Bezeichnung
    CD33 (CD33 Produkte)
    Synonyme
    SIGLEC-3 Protein, SIGLEC3 Protein, p67 Protein, Siglec-3 Protein, gp67 Protein, CD33 molecule Protein, CD33 antigen Protein, CD33 Protein, Cd33 Protein
    Hintergrund
    CD33, also known as myeloid cell surface antigen CD33 isoform 1, is a member of the Ig superfamily that is restricted to cells of the myelomonocytic lineage but whose functions and binding properties are unknown. It can function as a sialic acid-dependent cell adhesion molecule and that binding can be modulated by endogenous sialoglycoconjugates when it is expressed in a plasma membrane. It is usually considered myeloid-specific, but it can also be found on some lymphoid cells. It contains immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that are implicated in inhibition of cellular activity. It has been identified to modulate the risk of Alzheimer's disease (AD) in several recent genome-wide association studies (GWAS) in Caucasians. Recombinant human CD33, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
    Molekulargewicht
    54kDa (484aa) 50-70kDa (SDS-PAGE under reducing conditions)
    NCBI Accession
    NP_001763
    UniProt
    P20138
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