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TARBP2 Protein (AA 1-345)

Dieses Recombinant TARBP2-Protein wird in Escherichia coli (E. coli) exprimiert.
Produktnummer ABIN5853732

Kurzübersicht für TARBP2 Protein (AA 1-345) (ABIN5853732)

Target

Alle TARBP2 Proteine anzeigen
TARBP2 (TAR (HIV-1) RNA Binding Protein 2 (TARBP2))

Protein-Typ

Recombinant

Spezies

  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Quelle

  • 4
  • 2
  • 2
  • 2
  • 1
Escherichia coli (E. coli)

Applikation

SDS-PAGE (SDS)

Reinheit

> 85 % by SDS - PAGE
  • Proteineigenschaft

    AA 1-345

    Sequenz

    MLAANPGKTP ISLLQEYGTR IGKTPVYDLL KAEGQAHQPN FTFRVTVGDT SCTGQGPSKK AAKHKAAEVA LKHLKGGSML EPALEDSSSF SPLDSSLPED IPVFTAAAAA TPVPSVVLTR SPPMELQPPV SPQQSECNPV GALQELVVQK GWRLPEYTVT QESGPAHRKE FTMTCRVERF IEIGSGTSKK LAKRNAAAKM LLRVHTVPLD ARDGNEVEPD DDHFSIGVGS RLDGLRNRGP GCTWDSLRNS VGEKILSLRS CSLGSLGALG PACCRVLSEL SEEQAFHVSY LDIEELSLSG LCQCLVELST QPATVCHGSA TTREAARGEA ARRALQYLKI MAGSK
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  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Kommentare

    Denatured

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 10 % glycerol 0.4M urea

    Lagerung

    4 °C,-20 °C,-80 °C

    Informationen zur Lagerung

    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target

    TARBP2 (TAR (HIV-1) RNA Binding Protein 2 (TARBP2))

    Andere Bezeichnung

    TARBP2

    Hintergrund

    TARBP2 is a component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, EIF2C2/AGO2 and TARBP2. This protein contains 3 DRBM (double-stranded RNA-binding) domains. It may also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1. TARBP2 binds to the HIV-1 TAR RNA which is located in the long terminal repeat (LTR) of HIV-1, and stimulates translation of TAR-containing RNAs. Recombinant human TARBP2 protein was expressed in E.coli.

    Molekulargewicht

    36.9 kDa (345aa)

    NCBI Accession

    NP_004169

    UniProt

    Q15633

    Pathways

    Regulatorische RNA Pathways, Ribonucleoprotein Complex Subunit Organization
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