RCC1 Protein

Produktnummer ABIN5776891

Recombinant RCC1-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für RCC1 Protein (ABIN5776891)

Target: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 90 % (SDS-PAGE)

Produktdetails

Verwendungszweck: RCC1 (RanGEF), Regulator of Chromosome Condensation, Ran Guanine Exchange Factor, human, recombinant, E. coli

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied in 20 mM HEPES pH 7.650 mM NaCl and 2 mM DTE

Handhabung: Please centrifuge briefly before opening (volume ≤2 ml).,avoid freeze/thaw cycles

Lagerung: -80 °C

Informationen zur Lagerung: store at -80 °C avoid freeze/thaw cycles

Haltbarkeit: 12 months

Antigendetails

Target: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Andere Bezeichnung: RCC1 (RanGEF)

Hintergrund: RCC1 (Regulator of Chromosome Condensation, a β propeller chromatin-bound protein) catalyzes guanine nucleotide exchange of the Ras-related nuclear protein Ran. RCC1 is the guanine nucleotide exchange factor (GEF) for Ran which induces exchange between the bound GDP and cellular GTP. Genetic studies have suggested that RCC1 may be involved in sensing the replication state of DNA and controlling the activation of Cdc2/cyclin B protein kinase through Ran.

Molekulargewicht: 44.97 kDa (421 amino acids)

Pathways: Chromatin Binding, Protein targeting to Nucleus