RAB5 Protein

Produktnummer ABIN5776883

Dieses Recombinant RAB5-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für RAB5 Protein (ABIN5776883)

Target: RAB5 (RAB5A) (RAB5A, Member RAS Oncogene Family (RAB5A))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Ratte

Quelle: Escherichia coli (E. coli)

Reinheit: > 90 % (SDS-PAGE)

Produktdetails

Verwendungszweck: Rab5A, Ras-associated, small GTP-binding protein, rat, recombinant, E. coli

Biological Activity Comment: 100 pmol of protein can bind > 80 pmol of GDP.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied in 25 mM HEPES pH 7.240 mM NaCl2 mM MgCl210 μM GDP and 3 mM TCEP

Handhabung: Please centrifuge briefly before opening (volume ≤2 ml).,avoid freeze/thaw cycles

Lagerung: -80 °C

Informationen zur Lagerung: store at -80 °C avoid freeze/thaw cycles

Haltbarkeit: 12 months

Antigendetails

Target: RAB5 (RAB5A) (RAB5A, Member RAS Oncogene Family (RAB5A))

Andere Bezeichnung: Rab5A

Hintergrund: Rab5A is a small GTPase that belongs to the Ras superfamily. Rab proteins play an important role in various aspects of membrane traffic, including cargo selection, vesicle budding, vesicle motility, tethering, docking, and fusion. The small Rab5A GTPase is localized to plasma membrane, clathrin coated vesicles, caveosomes and early endosomes. Rab5 is a key regulator of the early endocytic pathway and plays a role in early endosome fusion and caveolar vesicle targeting to early endosomes. Furtermore it is also implicated in EGF receptor activation and apoptotic cell engulfment.

Molekulargewicht: 24 kDa

NCBI Accession: NP_073183

Pathways: Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity