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MLKL Protein (AA 1-471, full length) (His tag)

MLKL Spezies: Human Wirt: Hefe Recombinant > 90 % SDS
Produktnummer ABIN5714442
  • Target Alle MLKL Proteine anzeigen
    MLKL (Mixed Lineage Kinase Domain-Like (MLKL))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    full length, AA 1-471
    Spezies
    • 5
    • 2
    Human
    Quelle
    • 2
    • 2
    • 2
    • 1
    Hefe
    Aufreinigungstag / Konjugat
    Dieses MLKL Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Sequenz
    MENLKHIITL GQVIHKRCEE MKYCKKQCRR LGHRVLGLIK PLEMLQDQGK RSVPSEKLTT AMNRFKAALE EANGEIEKFS NRSNICRFLT ASQDKILFKD VNRKLSDVWK ELSLLLQVEQ RMPVSPISQG ASWAQEDQQD ADEDRRAFQM LRRDNEKIEA SLRRLEINMK EIKETLRQYL PPKCMQEIPQ EQIKEIKKEQ LSGSPWILLR ENEVSTLYKG EYHRAPVAIK VFKKLQAGSI AIVRQTFNKE IKTMKKFESP NILRIFGICI DETVTPPQFS IVMEYCELGT LRELLDREKD LTLGKRMVLV LGAARGLYRL HHSEAPELHG KIRSSNFLVT QGYQVKLAGF ELRKTQTSMS LGTTREKTDR VKSTAYLSPQ ELEDVFYQYD VKSEIYSFGI VLWEIATGDI PFQGCNSEKI RKLVAVKRQQ EPLGEDCPSE LREIIDECRA HDPSVRPSVD EILKKLSTFS K
    Aufreinigung
    SDS-PAGE
    Reinheit
    > 90 %
    Top Product
    Discover our top product MLKL Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Lagerung
    -80 °C,4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    MLKL (Mixed Lineage Kinase Domain-Like (MLKL))
    Andere Bezeichnung
    MLKL (MLKL Produkte)
    Synonyme
    MLKL Protein, 9130019I15Rik Protein, mixed lineage kinase domain like pseudokinase Protein, mixed lineage kinase domain-like Protein, MLKL Protein, mlkl Protein, Mlkl Protein
    Hintergrund
    Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma mbrane and execution of programmed necrosis characterized by calcium influx and plasma mbrane damage. Does not have protein kinase activity.
    Molekulargewicht
    56.48 kDa
    UniProt
    Q8NB16
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