GPR161 Protein (AA 1-28, Extracellular, partial) (GST tag)
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- Target Alle GPR161 Proteine anzeigen
- GPR161 (G Protein-Coupled Receptor 161 (GPR161))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- Extracellular, AA 1-28, partial
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses GPR161 Protein ist gelabelt mit GST tag.
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- MSLNSSLSCR KELSNLTEEE GGEGGVII
- Aufreinigung
- SDS-PAGE
- Reinheit
- > 90 %
- Top Product
- Discover our top product GPR161 Protein
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G Protein-Coupled Receptor 161 (GPR161) (AA 362-460) protein (GST tag)
GPR161 Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AP, AA
G Protein-Coupled Receptor 161 (GPR161) (AA 328-529) protein (His tag)Crystallography grade GPR161 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
G Protein-Coupled Receptor 161 (GPR161) (AA 344-545) protein (His tag)Crystallography grade GPR161 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB, Crys
G Protein-Coupled Receptor 161 (GPR161) (AA 1-529) protein (Strep Tag)Crystallography grade GPR161 Spezies: Human Wirt: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
G Protein-Coupled Receptor 161 (GPR161) (AA 1-545) protein (Strep Tag)Crystallography grade GPR161 Spezies: Maus Wirt: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
G Protein-Coupled Receptor 161 (GPR161) (AA 1-28), (partial) protein (GST tag)GPR161 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant 90 % ELISA
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Lagerung
- -80 °C,4 °C,-20 °C
- Informationen zur Lagerung
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- GPR161 (G Protein-Coupled Receptor 161 (GPR161))
- Andere Bezeichnung
- GP161 (GPR161 Produkte)
- Synonyme
- RE2 Protein, Gm208 Protein, Gm208Gpr Protein, vl Protein, RGD1563245 Protein, si:bz20i5.4 Protein, si:rp71-20i5.4 Protein, G protein-coupled receptor 161 Protein, GPR161 Protein, Gpr161 Protein, gpr161 Protein
- Hintergrund
- Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is roved from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown .
- Molekulargewicht
- 30.4 kDa
- UniProt
- Q8N6U8
- Pathways
- cAMP Metabolic Process
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