HIST1H2BN Protein (AA 2-126) (His-SUMO Tag)

Produktnummer ABIN5711721

Produktdetails

Target: HIST1H2BN (Histone H2B Type 1-N (HIST1H2BN))

Protein-Typ: Recombinant

Proteineigenschaft: AA 2-126

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses HIST1H2BN Protein ist gelabelt mit His-SUMO Tag.

Applikation: SDS-PAGE (SDS)

Sequenz: PEPSKSAPAP KKGSKKAVTK AQKKDGKKRK RSRKESYSVY VYKVLKQVHP DTGISSKAMG IMNSFVNDIF ERIAGEASRL AHYNKRSTIT SREIQTAVRL LLPGELAKHA VSEGTKAVTK YTSSK

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: HIST1H2BN (Histone H2B Type 1-N (HIST1H2BN))

Andere Bezeichnung: H2B1N (HIST1H2BN Produkte)

Synonyme: H2B/d Protein, H2BFD Protein, HIST1H2BM Protein, HIST1H2BN Protein, histone cluster 1 H2B family member n Protein, histone cluster 1, H2bn Protein, HIST1H2BN Protein, Hist1h2bn Protein, HIST1H2BB Protein

Hintergrund: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a tplate. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome rodeling.

Molekulargewicht: 29.78 kDa

UniProt: Q99877