Gag (AA 216-478) protein (GST tag)

Produktnummer ABIN5710990

Dieses Recombinant -Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für Gag (AA 216-478) protein (GST tag) (ABIN5710990)

Target: Gag

Protein-Typ: Recombinant

Spezies: Moloney Murine Leukemia Virus (MoMuLV)

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 90 %

Produktdetails

Proteineigenschaft: AA 216-478

Aufreinigungstag / Konjugat: GST tag

Sequenz: PLRAGGNGQL QYWPFSSSDL YNWKNNNPSF SEDPGKLTAL IESVLITHQP TWDDCQQLLG TLLTGEEKQR VLLEARKAVR GDDGRPTQLP NEVDAAFPLE RPDWDYTTQA GRNHLVHYRQ LLLAGLQNAG RSPTNLAKVK GITQGPNESP SAFLERLKEA YRRYTPYDPE DPGQETNVSM SFIWQSAPDI GRKLERLEDL KNKTLGDLVR EAEKIFNKRE TPEEREERIR RETEEKEERR RTEDEQKEKE RDRRRHREMS KLL

Aufreinigung: SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: Gag

Substanzklasse: Viral Protein

Hintergrund: Gag polyprotein plays a role in budding and is processed by the viral protease during virion maturation outside the cell. During budding, it recruits, in a PPXY-dependent or independent manner, Nedd4-like ubiquitin ligases that conjugate ubiquitin molecules to Gag, or to Gag binding host factors. Interaction with HECT ubiquitin ligases probably link the viral protein to the host ESCRT pathway and facilitate release.

Molekulargewicht: 58 kDa

UniProt: P03332