Bovine Coronavirus Spike Protein (AA 326-540, partial) (His tag)

Produktnummer ABIN5710878

Produktdetails

Target: Bovine Coronavirus Spike (BCoV S) (Bovine Coronavirus Spike Protein (BCoV S))

Protein-Typ: Recombinant

Proteineigenschaft: AA 326-540, partial

Spezies: Bovine Coronavirus (BCoV)

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Bovine Coronavirus Spike Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: PNLPDCNIEA WLNDKSVPSP LNWERKTFSN CNFNMSSLMS FIQADSFTCN NIEAAKIYGM CFSSITIDKF AIPNGRKVDL QLGNLGYLQS FNYRIDTTAA SCQLYYNLPA ANVSVSRFNP STWNRRFGFT EQSVFKPQPV GVFTHHDVVY AQHCFKAPTN FCPCKLDGSL CVGNGPGIDA GYKNSGIGTC PAGTNYLTCH NAAQCDCLCT PDPIT

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: Bovine Coronavirus Spike (BCoV S) (Bovine Coronavirus Spike Protein (BCoV S))

Andere Bezeichnung: Bovine Corona Virus Peplomer Protein (BCoV S Produkte)

Substanzklasse: Viral Protein

Hintergrund: S1 attaches the virion to the cell mbrane by binding to 9-O-acetylated sialic acid containing proteins, initiating the infection.S2 is a class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell mbrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell mbranes .

Molekulargewicht: 27.7 kDa

UniProt: P25194