WT1 Protein (AA 1-449, full length)

Produktnummer ABIN5710628

Dieses Recombinant WT1-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für WT1 Protein (AA 1-449, full length) (ABIN5710628)

Target: WT1 (Wilms Tumor 1 (WT1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Produktdetails

Proteineigenschaft: AA 1-449, full length

Verwendungszweck: Recombinant Human Wilms tumor protein(WT1)

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1-2 mg/mL

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Haltbarkeit: 6-12 months

Antigendetails

Target: WT1 (Wilms Tumor 1 (WT1))

Andere Bezeichnung: WT1

Hintergrund: Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital syst. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.

Pathways: Tube Formation