SAMHD1 Protein (AA 395-626) (His tag)

Produktnummer ABIN5710314

Produktdetails

Target: SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 395-626

Spezies: Maus

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses SAMHD1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: DIMITDAFLK ADPYVEITGT AGKKFRISTA IDDMEAFTKL TDNIFLEVLH STDPQLSEAQ SILRNIECRN LYKYLGETQP KREKIRKEEY ERLPQEVAKA KPEKAPDVEL KAEDFIVDVI NVDYGMEDKN PIDRVHFYCK SNSKQAVRIN KEQVSQLLPE KFAEQLIRVY CKKKDGKSLD AAGKHFVQWC ALRDFTKPQD GDIIAPLITP LKWNNKTSSC LQEVSKVKTC LK

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

Andere Bezeichnung: SAMH1 (SAMHD1 Produkte)

Synonyme: CHBL2 Protein, DCIP Protein, HDDC1 Protein, MOP-5 Protein, SBBI88 Protein, si:dkeyp-44b8.8 Protein, E330031J07Rik Protein, Mg11 Protein, SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 Protein, SAM domain and HD domain 1 Protein, SAM domain and HD domain, 1 Protein, SAMHD1 Protein, samhd1 Protein, Samhd1 Protein

Hintergrund: Host restriction nuclease that blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May function by reducing the cellular dNTP levels to levels too low for retroviral reverse transcription to occur. May play a role in mediating proinflammatory responses to TNF-alpha signaling .

Molekulargewicht: 30.7 kDa

UniProt: Q60710