Reelin Protein (RELN) (AA 26-254, partial) (His tag)

Produktnummer ABIN5710244

Produktdetails

Target: Reelin (RELN)

Protein-Typ: Recombinant

Proteineigenschaft: AA 26-254, partial

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Reelin Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: AAGYYPRFSP FFFLCTHHGE LEGDGEQGEV LISLHIAGNP TYYVPGQEYH VTISTSTFFD GLLVTGLYTS TSVQASQSIG GSSAFGFGIM SDHQFGNQFM CSVVASHVSH LPTTNLSFIW IAPPAGTGCV NFMATATHRG QVIFKDALAQ QLCEQGAPTD VTVHPHLAEI HSDSIILRDD FDSYHQLQLN PNIWVECNNC ETGEQCGAIM HGNAVTFCEP YGPRELITT

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: Reelin (RELN)

Andere Bezeichnung: RELN (RELN Produkte)

Hintergrund: Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it ses to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation .

Molekulargewicht: 29 kDa

UniProt: P78509

Pathways: Synaptic Membrane