tau Protein (AA 2-752) (His tag)

Produktnummer ABIN5709913

Produktdetails

Target: tau (tau Protein)

Protein-Typ: Recombinant

Proteineigenschaft: AA 2-752

Spezies: Ratte

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses tau Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Sequenz: AEPRQEFDTM EDQAGDYTML QDQEGDMDHG LKESPPQPPA DDGSEEPGSE TSDAKSTPTA EDVTAPLVEE RAPDKQATAQ SHTEIPEGTT AEEAGIGDTP NMEDQAAGHV TQEPQKVEIF SQSLLVEPGR REGQAPDSGI SDWTHQQVPS MSGAPLPPQG LREATHQPLG TRPEDVERSH PASELLWQES PQKEAWGKDR LGSEEEVDED ITMDESSQES PPSQASLAPG TATPQARSVS ASGVSGETTS IPGFPAEGSI PLPADFFSKV SAETQASPPE GPGTGPSEEG HEAAPEFTFH VEIKASAPKE QDLEGATVVG APAEEQKARG PSVGKGTKEA SLLEPTDKQP AAGLPGRPVS RVPQLKARVA GVSKDRTGND EKKAKTSTPS CAKTPSNRPC LSPTRPTPGS SDPLIKPSSP AVCPEPATSP KYVSSVTPRN GSPGTKQMKL KGADGKTGAK IATPRGAATP GQKGTSNATR IPAKTTPSPK TPPGSGEPPK SGERSGYSSP GSPGTPGSRS RTPSLPTPPT REPKKVAVVR TPPKSPSASK SRLQTAPVPM PDLKNVRSKI GSTENLKHQP GGGKVQIINK KLDLSNVQSK CGSKDNIKHV PGGGSVHIVY KPVDLSKVTS KCGSLGNIHH KPGGGQVEVK SEKLDFKDRV QSKIGSLDNI THVPGGGNKK IETHKLTFRE NAKAKTDHGA EIVYKSPVVS GDTSPRHLSN VSSTGSIDMV DSPQLATLAD EVSASLAKQG L

Aufreinigung: SDS-PAGE

Reinheit: > 90 %

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: tau (tau Protein)

Andere Bezeichnung: tau (tau Produkte)

Synonyme: DDPAC Protein, FTDP-17 Protein, MAPTL Protein, MSTD Protein, MTBT1 Protein, MTBT2 Protein, PPND Protein, TAU Protein, tau Protein, PHF-tau Protein, microtubule associated protein tau Protein, MAPT Protein

Hintergrund: Promotes microtubule assbly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma mbrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Molekulargewicht: 82.5 kDa

UniProt: P19332