Integrin Alpha2b Protein (CD41) (AA 639-887, partial) (His-SUMO Tag)

Produktnummer ABIN5709771

Dieses Recombinant Integrin Alpha2b-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für Integrin Alpha2b Protein (CD41) (AA 639-887, partial) (His-SUMO Tag) (ABIN5709771)

Target: Integrin Alpha2b (CD41)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 90 %

Produktdetails

Proteineigenschaft: AA 639-887, partial

Aufreinigungstag / Konjugat: Dieses Integrin Alpha2b Protein ist gelabelt mit His-SUMO Tag.

Sequenz: CVPQLQLTAS VTGSPLLVGA DNVLELQMDA ANEGEGAYEA ELAVHLPQGA HYMRALSNVE GFERLICNQK KENETRVVLC ELGNPMKKNA QIGIAMLVSV GNLEEAGESV SFQLQIRSKN SQNPNSKIVL LDVPVRAEAQ VELRGNSFPA SLVVAAEEGE REQNSLDSWG PKVEHTYELH NNGPGTVNGL HLSIHLPGQS QPSDLLYILD IQPQGGLQCF PQPPVNPLKV DWGLPIPSPS PIHPAHHKR

Aufreinigung: SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Lagerung: -80 °C,4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Antigendetails

Target: Integrin Alpha2b (CD41)

Andere Bezeichnung: ITA2B

Hintergrund: Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.

Molekulargewicht: 42.97 kDa

UniProt: P08514

Pathways: Integrin Complex