CD47 Protein (CD47) (partial) (Fc Tag)

Produktnummer ABIN5608232

Recombinant CD47-Protein exprimiert in HEK-293 Cells.

Kurzübersicht für CD47 Protein (CD47) (partial) (Fc Tag) (ABIN5608232)

Target: CD47

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Applikation: Western Blotting (WB)

Reinheit: >95 % as determined by SDS-PAGE.

Produktdetails

Proteineigenschaft: partial

Aufreinigungstag / Konjugat: Dieses CD47 Protein ist gelabelt mit Fc Tag.

Sequenz: Gln 19 - Lys 140

Endotoxin-Niveau: Endotoxin level is less than 1.0 EU per ug by the LAL method.

Anwendungsinformationen

Applikationshinweise: This recombinant protein can be used for WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 50 mM Tris, 100 mM Glycine, pH 7.5

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.

Antigendetails

Target: CD47

Andere Bezeichnung: CD47

Hintergrund: Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.

Molekulargewicht: 40 kDa

Gen-ID: 16423

UniProt: Q61735