CD28 Protein (CD28) (partial) (His tag)

Produktnummer ABIN5608228

Dieses Recombinant CD28-Protein wird in HEK-293 Cells exprimiert.

Kurzübersicht für CD28 Protein (CD28) (partial) (His tag) (ABIN5608228)

Target: CD28

Protein-Typ: Recombinant

Spezies: Maus

Quelle: HEK-293 Cells

Applikation: Western Blotting (WB)

Reinheit: >85 % as determined by SDS-PAGE.

Produktdetails

Proteineigenschaft: partial

Aufreinigungstag / Konjugat: Dieses CD28 Protein ist gelabelt mit His tag.

Sequenz: Asn 20 - Lys 149

Endotoxin-Niveau: Endotoxin level is less than 1.0 EU per ug by the LAL method.

Anwendungsinformationen

Applikationshinweise: This recombinant protein can be used for WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.

Antigendetails

Target: CD28

Andere Bezeichnung: CD28

Hintergrund: T-cell-specific surface glycoprotein CD28 is also known as TP44, is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2). When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.

Molekulargewicht: 17 kDa

Gen-ID: 12487

NCBI Accession: NP_031668

UniProt: P31041

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response