IL23A Protein
Kurzübersicht für IL23A Protein (ABIN5505700)
Target
Alle IL23A Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Applikation
Reinheit
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Spezifität
- Optimal preservation of protein structure, post-translational modifications and functions.
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Produktmerkmale
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- Recombinant human Interleukin-23 alpha / IL23A protein expressed in Insect cells.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
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Endotoxin-Niveau
- Less than 0.01 ng per μg protein as determined by the LAL method.
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Biological Activity Comment
- The ED50 is 0.5 - 0.8 ng/ml, corresponding to a specific activity of 1.25-2.0 x 10^6 units/mg, determined by mouse splenocytes IL-17A secretion induced by mIL-23 in a dose dependent manner. Under this assay, the bioactivity is equivalent
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Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- > 50 μg/mL
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Buffer
- 1 x PBS
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Lagerung
- -80 °C
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Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- IL23A (Interleukin 23, alpha subunit p19 (IL23A))
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Andere Bezeichnung
- Interleukin-23 alpha / IL23A
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Molekulargewicht
- 55.4 kDa
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NCBI Accession
- NP_112542
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
Target
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