nectin-3 Protein (AA 58-400) (His tag)
Kurzübersicht für nectin-3 Protein (AA 58-400) (His tag) (ABIN4949137)
Target
Alle nectin-3 (NECTIN3) Proteine anzeigenProtein-Typ
Spezies
Quelle
Applikation
Reinheit
-
-
Proteineigenschaft
- AA 58-400
-
Aufreinigungstag / Konjugat
- Dieses nectin-3 Protein ist gelabelt mit His tag.
-
Sequenz
- AA 58-400
-
Produktmerkmale
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 39.6 kDa. The protein migrates as 60-75 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
-
Endotoxin-Niveau
- Less than 1.0 EU per μg by the LAL method.
-
-
Möchten Sie weitere Optionen für dieses Protein ?
!Entdecken Sie unsere vordefinierten maßgeschneiderten Proteine und Proteinservices!Ihr Projekt erfordert weitere Anpassungen? Kontaktieren Sie uns und entdecken Sie unsere maßgeschneiderten Proteinlösungen
-
Nectin cell adhesion molecule 3 (NECTIN3) (AA 58-400) (Active) protein (His-Avi Tag)
NECTIN3 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Nectin cell adhesion molecule 3 (NECTIN3) (AA 58-400) (Active) protein (Biotin,His-Avi Tag)NECTIN3 Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Nectin cell adhesion molecule 3 (NECTIN3) (AA 58-400) (Active) protein (Fc Tag,AVI tag,Biotin)NECTIN3 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Nectin cell adhesion molecule 3 (NECTIN3) (AA 58-400) (Active) protein (Fc Tag)NECTIN3 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
Nectin cell adhesion molecule 3 (NECTIN3) (AA 1-366) protein (GST tag)NECTIN3 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Nectin cell adhesion molecule 3 (NECTIN3) (AA 58-404) protein (His tag)NECTIN3 Spezies: Human Wirt: Baculovirus infected Insect Cells Recombinant > 90 % SDS
-
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Buffer
- PBS, pH 7.4
-
Handhabung
- Please avoid repeated freeze-thaw cycles.
-
Lagerung
- -20 °C
-
-
- nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))
-
Andere Bezeichnung
- Nectin-3
-
Hintergrund
- Poliovirus receptor-related 3 (PVRL3), also known as nectin-3 and CD113, is a human protein of the immunoglobulin superfamily which forms part of adherens junctions. Nectins are immunoglobulin-like adhesion molecules that interact with afadin (AF6, MIM 159559). Afadin is an actin filament-binding protein that connects nectins to the actin cytoskeleton. The nectin-afadin system organizes adherens junctions cooperatively with the cadherin system in epithelial cells. PVRL3 plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with PVRL2/nectin-2 at Sertoli-spermatid junctions. Furthermore, PVRL3 induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation.
-
Molekulargewicht
- 39.6 kDa
-
UniProt
- Q9NQS3
-
Pathways
- Cell-Cell Junction Organization
Target
-
