VEGF110 (AA 27-136) (Active) Protein

Produktnummer ABIN4948990

Dieses Recombinant -Protein wird in HEK-293 Cells exprimiert.

Kurzübersicht für VEGF110 (AA 27-136) (Active) Protein (ABIN4948990)

Target: VEGF110

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: HEK-293 Cells

Applikation: Functional Studies (Func)

Reinheit: >95 % as determined by SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 27-136

Marke: ActiveMax®

Sequenz: AA 27-136

Produktmerkmale: This protein carries no "tag". The protein has a calculated MW of 12.6 kDa. As a result of glycosylation, the protein migrates as 18-20 kDa under reducing (R) condition, and 40-45 kDa (homodimer) under non-reducing (NR) condition (SDS-PAGE).

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Handhabung: Please avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Antigendetails

Target: VEGF110

Hintergrund: Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, and is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. Alternatively spliced isoforms of 110,121,145,165,183,189 and 206 amino acids in length are expressed in humans.

Molekulargewicht: 12.7 kDa

NCBI Accession: NP_001165097