Advanced Glycosylation End Product (AGE) Protein

Details zu Produkt Nr. ABIN3209853
Proteinname
Spezies
General
1
1
Wirt
2
Protein-Typ
Native
Applikation
Immunoprecipitation (IP), SDS-PAGE (SDS), ELISA, Western Blotting (WB)
Optionen
Spezifität An advanced glycation end-product (AGE) is the result of a chain of chemical reactions after an initial glycation reaction. Glycation is accomplished by the Maillard reaction, which is a multistep process that begins with Schiff base formation between the amine and the carbonyl group on the sugar followed by rearrangement to form Amadori intermediates. AGEs affect nearly every type of cell and molecule in the body, and are thought to be one factor in aging and some age-related chronic diseases. They are also believed to play a causative role in the vascular complications of diabetes mellitus
Reinheit > 90 %
Endotoxin-Niveau < 1.0 EU per 1 µg (determined by the LAL method)
Proteinname
Hintergrund An advanced glycation end-product (AGE) is the result of a chain of chemical reactions after an initial glycation reaction. Glycation is accomplished by the Maillard reaction, which is a multistep process that begins with Schiff base formation between the amine and the carbonyl group on the sugar followed by rearrangement to form Amadori intermediates. AGEs affect nearly every type of cell and molecule in the body, and are thought to be one factor in aging and some age-related chronic diseases. They are also believed to play a causative role in the vascular complications of diabetes mellitus
Kommentare

The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 °C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Reconstitute in sterile PBS, pH 7.2 - pH 7.4.
Buffer Supplied as lyophilized form in 50 mM TRIS, 200 mM NaCl
Handhabung Avoid repeated freeze/thaw cycles.
Lagerung 4 °C
Informationen zur Lagerung Store at 2-8 °C for one month. Aliquot and store at -80 °C for 12 months.