Nerve Growth Factor Protein (NGF) (AA 122-241)

Produktnummer ABIN2830300

Dieses Recombinant Nerve Growth Factor-Protein wird in Mammalian Cells produziert.

Kurzübersicht für Nerve Growth Factor Protein (NGF) (AA 122-241) (ABIN2830300)

Target: Nerve Growth Factor (NGF)

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Mammalian Cells

Applikation: Functional Studies (Func)

Reinheit: >90 % as determined by SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 122-241

Sequenz: Ser122-Ala241, Accession # CAA36832

Produktmerkmale: Biological Activity: The ED50, as determined by a cell proliferation assay using human TF-1 cells, is less than 2 ng/mL.

Sterilität: 0.2 μm filtered

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.2 % acetic acid

Lagerung: -20 °C

Antigendetails

Target: Nerve Growth Factor (NGF)

Andere Bezeichnung: NGF

Hintergrund: Relevance: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177). {ECO:0000269|PubMed:20164177}.
Synonyms: Beta-NGF,

Molekulargewicht: 13.5 kDa

UniProt: P01138

Pathways: Regulation of Cell Size