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VEGF 165 (Active) Protein

This anti- antibody (ABIN2746009) is a Escherichia coli (E. coli) antibody detecting in SDS. Suitable for Human.
Produktnummer ABIN2746009

Kurzübersicht für VEGF 165 (Active) Protein (ABIN2746009)

Target

VEGF 165

Protein-Typ

Recombinant

Biologische Aktivität

Active

Spezies

  • 19
  • 2
  • 1
Human

Quelle

  • 9
  • 7
  • 2
  • 1
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Applikation

SDS-PAGE (SDS)

Reinheit

>95 % (SDS-PAGE)
  • Verwendungszweck

    VEGF 165 (human) (rec.)

    Kreuzreaktivität

    Human

    Produktmerkmale

    Human VEGF 165 (165aa).

    Endotoxin-Niveau

    <0.1ng/μg protein.

    Biological Activity Comment

    The ED50 for stimulation of cell proliferation in human umbilical vein endothelial cells by VEGF 165 has been determined to be in the range of 1-5ng/ml.
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  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Reconstitute with 50 mM acetic acid to a concentration not lower than 50 μg/mL.

    Handhabung

    After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. For long term storage we recommend to add at least 0.1 % human or bovine serum albumin.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Short Term Storage: +4°C

    Long Term Storage: -20°C

    Use & Stability: Stable for at least 6 months after receipt when stored at -20°C.

    Haltbarkeit

    6 months
  • Target

    VEGF 165

    Hintergrund

    Vascular Endothelial Growth Factor, VEGF-A, VPF

    Human vascular endothelial growth factor (VEGF 165) is produced as a homodimer. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. VEGF 165 is a specific mitogen for vascular endothelial cells and a strong angiogenic factor in vivo. In addition to its action as a mitogen it is a potent vascular permeability factor (VPF) in vivo. It is also a chemoattractant molecule for monocytes and endothelial cells. It induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels.

    Molekulargewicht

    ~38.2kDa

    UniProt

    P15692-4
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