VEGF 165 (Active) Protein
Kurzübersicht für VEGF 165 (Active) Protein (ABIN2746009)
Target
Protein-Typ
Biologische Aktivität
Spezies
Quelle
Applikation
Reinheit
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    - 
                                            Verwendungszweck
- VEGF 165 (human) (rec.)
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                                            Kreuzreaktivität
- Human
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                                            Produktmerkmale
- Human VEGF 165 (165aa).
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                                            Endotoxin-Niveau
- <0.1ng/μg protein.
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                                            Biological Activity Comment
- The ED50 for stimulation of cell proliferation in human umbilical vein endothelial cells by VEGF 165 has been determined to be in the range of 1-5ng/ml.
 
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                                            Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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    - 
                                            Format
- Lyophilized
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                                            Rekonstitution
- Reconstitute with 50 mM acetic acid to a concentration not lower than 50 μg/mL.
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                                            Handhabung
- After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. For long term storage we recommend to add at least 0.1 % human or bovine serum albumin.
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                                            Lagerung
- 4 °C,-20 °C
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                                            Informationen zur Lagerung
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                        Short Term Storage: +4°C Long Term Storage: -20°C Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. 
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                                            Haltbarkeit
- 6 months
 
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    - VEGF 165
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                                            Hintergrund
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                        Vascular Endothelial Growth Factor, VEGF-A, VPF Human vascular endothelial growth factor (VEGF 165) is produced as a homodimer. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. VEGF 165 is a specific mitogen for vascular endothelial cells and a strong angiogenic factor in vivo. In addition to its action as a mitogen it is a potent vascular permeability factor (VPF) in vivo. It is also a chemoattractant molecule for monocytes and endothelial cells. It induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. 
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                                            Molekulargewicht
- ~38.2kDa
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                                            UniProt
- P15692-4
 Target
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