STIP1 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2732854

Dieses Recombinant STIP1-Protein wird in HEK-293 Cells exprimiert.

Kurzübersicht für STIP1 Protein (Myc-DYKDDDDK Tag) (ABIN2732854)

Target: STIP1 (Stress-Induced-phosphoprotein 1 (STIP1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Applikation: Antibody Production (AbP), Standard (STD)

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Produktdetails

Aufreinigungstag / Konjugat: Dieses STIP1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Produktmerkmale:

• Recombinant human STIP1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: STIP1 (Stress-Induced-phosphoprotein 1 (STIP1))

Andere Bezeichnung: Stip1

Hintergrund: STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A MIM 140550) and HSP90 (see HSP90AA1 MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009]

Molekulargewicht: 62.5 kDa

NCBI Accession: NP_006810