SPATA18 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2732514

Produktdetails

Target: SPATA18 (Spermatogenesis Associated 18 (SPATA18))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses SPATA18 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human SPATA18 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: SPATA18 (Spermatogenesis Associated 18 (SPATA18))

Andere Bezeichnung: Spata18 (SPATA18 Produkte)

Synonyme: Mieap Protein, SPETEX1 Protein, 1700067I02Rik Protein, MIEAP Protein, spetex-1 Protein, mieap Protein, spetex1 Protein, im:7140046 Protein, zgc:110352 Protein, spermatogenesis associated 18 Protein, spermatogenesis associated 18 L homeolog Protein, SPATA18 Protein, Spata18 Protein, spata18.L Protein, spata18 Protein

Hintergrund: This gene encodes a p53-inducible protein that is able to induce lysosome-like organelles within mitochondria that eliminate oxidized mitochondrial proteins, thereby contributing to mitochondrial quality control. Dysregulation of mitochondrial quality control is associated with cancer and degenerative diseases. The encoded protein mediates accumulation of the lysosome-like mitochondrial organelles through interaction with B cell lymphoma 2 interacting protein 3 and B cell lymphoma 2 interacting protein 3 like at the outer mitochondrial membrane, which allows translocation of lysosomal proteins to the mitochondrial matrix from the cytosol. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 60.9 kDa

NCBI Accession: NP_660306