Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

SAA1 Protein (Transcript Variant 1)

SAA1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining Func, AbP, STD, PI Active
Produktnummer ABIN2731847
  • Target Alle SAA1 Proteine anzeigen
    SAA1 (Serum Amyloid A1 (SAA1))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    Transcript Variant 1
    Spezies
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 10
    • 8
    • 2
    • 1
    Escherichia coli (E. coli)
    Applikation
    Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)
    Spezifität
    Optimal preservation of protein structure, post-translational modifications and functions.
    Produktmerkmale
    • Recombinant human Serum amyloid A1 (SAA1), transcript variant 1. (transcript variant 1) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    Reinheit
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    Endotoxin-Niveau
    Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
    Biological Activity Comment
    Tested by its ability to down-regulate lipid biosynthesis in aortic smooth muscle cells. The effective concentration was found to be 4 uM.* * Schreiber, BM. et al. Biochem J. 1999 Nov 15 344 Pt 1:7-13
    Top Product
    Discover our top product SAA1 Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
    Handhabung
    Resuspend the protein in the desired concentration in proper buffer
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    SAA1 (Serum Amyloid A1 (SAA1))
    Abstract
    SAA1 Produkte
    Synonyme
    PIG4 Protein, SAA Protein, SAA2 Protein, TP53I4 Protein, zgc:103580 Protein, SAA1 Protein, Saa-1 Protein, Saa2 Protein, serum amyloid A1 Protein, serum amyloid A Protein, amyloid protein A Protein, serum amyloid A protein Protein, serum amyloid a protein Protein, serum amyloid A 1 Protein, serum amyloid protein A Protein, SAA1 Protein, saa Protein, LOC694827 Protein, Sden_2438 Protein, Mmc1_0571 Protein, Riean_0971 Protein, Saa1 Protein, LOC100009168 Protein, LOC101120204 Protein
    Hintergrund
    This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11.
    Molekulargewicht
    12 kDa
    NCBI Accession
    NP_000322
    Pathways
    Toll-Like Receptors Cascades
Sie sind hier:
Kundenservice