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Senataxin (SETX) protein (Myc-DYKDDDDK Tag)

Recombinant -Protein exprimiert in HEK-293T Cells.
Produktnummer ABIN2731631

Kurzübersicht für Senataxin (SETX) protein (Myc-DYKDDDDK Tag) (ABIN2731631)

Target

Senataxin (SETX)

Protein-Typ

Recombinant

Spezies

Human

Quelle

  • 1
HEK-293T Cells

Applikation

Antibody Production (AbP), Standard (STD)

Reinheit

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Aufreinigungstag / Konjugat

    Myc-DYKDDDDK Tag

    Produktmerkmale

    • Recombinant human Senataxin (SETX) protein expressed in HEK293 cell.
    • Produced with end-sequenced ORF clone
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  • Applikationshinweise

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    50 μg/mL

    Buffer

    25 mM Tris-HCl, pH 7.3, 100 mM glycine, and 10 % glycerol.

    Lagerung

    -80 °C

    Informationen zur Lagerung

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    Senataxin (SETX)

    Hintergrund

    This gene encodes a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activity encoded by a domain at the C-terminal end of the protein. The protein encoded by this gene contains a DNA/RNA helicase domain at its C-terminal end which suggests that it may be involved in both DNA and RNA processing. Mutations in this gene have been associated with ataxia-ocular apraxia-2 (AOA2) and an autosomal dominant form of juvenile amyotrophic lateral sclerosis (ALS4).

    Molekulargewicht

    57.8 kDa

    NCBI Accession

    NP_055861
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