RASSF5 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2730567

Produktdetails

Target: RASSF5 (Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 3

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses RASSF5 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human RASSF5 / NORE1 (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: RASSF5 (Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5))

Andere Bezeichnung: Rassf5,nore1 (RASSF5 Produkte)

Synonyme: Maxp1 Protein, NORE1 Protein, NORE1A Protein, NORE1B Protein, RAPL Protein, RASSF3 Protein, 1300019G20Rik Protein, AU042887 Protein, Nore1 Protein, Nore1A Protein, Nore1B Protein, Rapl Protein, Ras association domain family member 5 Protein, Ras association (RalGDS/AF-6) domain family member 5 Protein, RASSF5 Protein, Rassf5 Protein

Hintergrund: This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 30.2 kDa

NCBI Accession: NP_872606

Pathways: T-Zell Rezeptor Signalweg