RASGRP2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2730541

Produktdetails

Target: RASGRP2 (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 2

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses RASGRP2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human RASGRP2 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: RASGRP2 (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))

Andere Bezeichnung: Rasgrp2 (RASGRP2 Produkte)

Synonyme: CALDAG-GEFI Protein, CDC25L Protein, xrasgrp2 Protein, RASGRP2 Protein, Caldaggef1 Protein, CalDAG-GEFI Protein, rasgrp2 Protein, RAS guanyl releasing protein 2 Protein, RAS guanyl releasing protein 2 (calcium and DAG-regulated) S homeolog Protein, RAS, guanyl releasing protein 2 Protein, RAS guanyl releasing protein 2 (calcium and DAG-regulated) L homeolog Protein, RASGRP2 Protein, rasgrp2.S Protein, Rasgrp2 Protein, rasgrp2.L Protein

Hintergrund: The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Four alternatively spliced transcript variants encoding two different isoforms have been found for this gene.

Molekulargewicht: 69.1 kDa

NCBI Accession: NP_722541

Pathways: T-Zell Rezeptor Signalweg