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PSME2 Protein (Myc-DYKDDDDK Tag)

PSME2 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2730010
  • Target Alle PSME2 Proteine anzeigen
    PSME2 (Proteasome (Prosome, Macropain) Activator Subunit 2 (PA28 Beta) (PSME2))
    Protein-Typ
    Recombinant
    Spezies
    • 5
    • 1
    • 1
    Human
    Quelle
    • 4
    • 2
    • 2
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses PSME2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human PSME2 / REG-beta protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PSME2 Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PSME2 (Proteasome (Prosome, Macropain) Activator Subunit 2 (PA28 Beta) (PSME2))
    Andere Bezeichnung
    Psme2,reg-beta (PSME2 Produkte)
    Synonyme
    unp309 Protein, PA28B Protein, PA28beta Protein, REGbeta Protein, AA589371 Protein, AI788882 Protein, PA28b Protein, proteasome activator subunit 2 Protein, proteasome (prosome, macropain) activator subunit 2 (PA28 beta) Protein, psme2 Protein, PSME2 Protein, Psme2 Protein
    Hintergrund
    The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the beta subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three beta and three alpha subunits combine to form a heterohexameric ring. Six pseudogenes have been identified on chromosomes 4, 5, 8, 10 and 13.
    Molekulargewicht
    27.2 kDa
    NCBI Accession
    NP_002809
    Pathways
    Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA
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