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PAK7 Protein (Transcript Variant 2)

Dieses Recombinant PAK7-Protein wird in Escherichia coli (E. coli) exprimiert.
Produktnummer ABIN2728183

Kurzübersicht für PAK7 Protein (Transcript Variant 2) (ABIN2728183)

Target

Alle PAK7 Proteine anzeigen
PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))

Protein-Typ

Recombinant

Biologische Aktivität

Active

Spezies

  • 4
  • 2
  • 1
Human

Quelle

  • 3
  • 2
  • 1
  • 1
Escherichia coli (E. coli)

Applikation

Antibody Production (AbP), Standard (STD), Functional Studies (Func), Protein Interaction (PI)

Reinheit

> 90 % as determined by SDS-PAGE and Coomassie blue staining
  • Proteineigenschaft

    Transcript Variant 2

    Spezifität

    Optimal preservation of protein structure, post-translational modifications and functions.

    Produktmerkmale

    • Recombinant human PAK7 / PAK5 (transcript variant 2) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.

    Endotoxin-Niveau

    <0.1 ng/μg of protein (<1EU/μg).

    Biological Activity Comment

    Specific activity was determined as 4,199 pmoles/min/μg, according to the Zlyte assay protocol
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    Produkt
    Expressionssystem
    Konjugat
    Origin
    Preis ab
    Expressionssystem HEK-293 Cells
    Konjugat His tag
    Origin Human
    Preis ab 13.711,36 €
    Expressionssystem Cell-free protein synthesis (CFPS)
    Konjugat Strep Tag
    Origin Human
    Preis ab 15.754,29 €

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  • Applikationshinweise

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1 mg/mL

    Buffer

    25 mM Tris-HCl pH 8.0, 150 mM NaCl, 10 % glycerol, 5 mM DTT.

    Lagerung

    -80 °C

    Informationen zur Lagerung

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))

    Andere Bezeichnung

    Pak7,pak5

    Hintergrund

    The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.

    Molekulargewicht

    33.9 kda

    NCBI Accession

    NP_817127
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