Neuroligin 3 Protein (NLGN3) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2727167

Recombinant Neuroligin 3-Protein exprimiert in HEK-293 Cells und wurde in 1 Publikation erwähnt.

Kurzübersicht für Neuroligin 3 Protein (NLGN3) (Myc-DYKDDDDK Tag) (ABIN2727167)

Target: Neuroligin 3 (NLGN3)

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Applikation: Antibody Production (AbP), Standard (STD)

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Produktdetails

Aufreinigungstag / Konjugat: Dieses Neuroligin 3 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Produktmerkmale:

• Recombinant human Neuroligin 3 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Referenzen

Venkatesh, Johung, Caretti, Noll, Tang, Nagaraja, Gibson, Mount, Polepalli, Mitra, Woo, Malenka, Vogel, Bredel, Mallick, Monje: "Neuronal Activity Promotes Glioma Growth through Neuroligin-3 Secretion." in: Cell, Vol. 161, Issue 4, pp. 803-16, (2015) (PubMed).

Antigendetails

Target: Neuroligin 3 (NLGN3)

Andere Bezeichnung: Neuroligin 3

Hintergrund: This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Molekulargewicht: 91.4 kDa

NCBI Accession: NP_061850

Pathways: Synaptic Membrane