MATK Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2725548

Produktdetails

Target: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 3

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses MATK Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human MATK (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Andere Bezeichnung: Matk (MATK Produkte)

Synonyme: si:ch211-63j24.2 Protein, CHK Protein, CTK Protein, HHYLTK Protein, HYL Protein, HYLTK Protein, Lsk Protein, Ntk Protein, Batk Protein, megakaryocyte-associated tyrosine kinase Protein, zinc finger RNA binding protein 2 Protein, matk Protein, MATK Protein, Matk Protein, ZFR2 Protein

Hintergrund: The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.

Molekulargewicht: 51.7 kDa

NCBI Accession: NP_647611