LZTS1 Protein (His tag)

Produktnummer ABIN2725087

Produktdetails

Target: LZTS1 (Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses LZTS1 Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human LZTS1 (full length, N-term HIS tag) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the N-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: LZTS1 (Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1))

Andere Bezeichnung: Lzts1 (LZTS1 Produkte)

Synonyme: F37 Protein, FEZ1 Protein, Psdzip70 Protein, LZTS1 Protein, f37 Protein, fez1 Protein, leucine zipper tumor suppressor 1 Protein, leucine zipper, putative tumor suppressor 1 Protein, LZTS1 Protein, Lzts1 Protein, lzts1 Protein

Hintergrund: This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.

Molekulargewicht: 66.4 kDa

NCBI Accession: NP_066300

Pathways: Synaptic Membrane