Leucine Rich Transmembrane and 0-Methyltransferase Domain Containing (LRTOMT) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2724964

Produktdetails

Target: Leucine Rich Transmembrane and 0-Methyltransferase Domain Containing (LRTOMT)

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Myc-DYKDDDDK Tag

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human LRTOMT / LRRC51 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: Leucine Rich Transmembrane and 0-Methyltransferase Domain Containing (LRTOMT)

Andere Bezeichnung: Lrtomt,lrrc51 (LRTOMT Produkte)

Synonyme: DFNB63 Protein, LRRC51 Protein, Lrtomt Protein, RGD1561509 Protein, lrrp51 Protein, lrtomt Protein, zgc:153736 Protein, leucine rich transmembrane and O-methyltransferase domain containing Protein, leucine-rich repeat-containing protein 51 Protein, leucine rich repeat containing 51 Protein, LRTOMT Protein, LRRC51 Protein, Lrtomt Protein, lrrc51 Protein

Hintergrund: This gene includes two transcript forms. The short form has one open reading frame (ORF), which encodes the leucine-rich repeats (LRR)-containing protein of unknown function. This protein is called LRTOMT1 or LRRC51. The long form has two alternative ORFs the upstream ORF has the same translation start codon as used in the short form and the resulting transcript is a candidate for nonsense-mediated decay, and the downstream ORF encodes a different protein, which is a transmembrane catechol-O-methyltransferase and is called LRTOMT2, TOMT or COMT2. The COMT2 is essential for auditory and vestibular function. Defects in the COMT2 can cause nonsyndromic deafness. Alternatively spliced transcript variants from each transcript form have been found for this gene.

Molekulargewicht: 22 kDa

NCBI Accession: NP_660352

Pathways: Sensory Perception of Sound