Lipin 1 Protein (LPIN1) (Myc-DYKDDDDK Tag)
Kurzübersicht für Lipin 1 Protein (LPIN1) (Myc-DYKDDDDK Tag) (ABIN2724880)
Target
Alle Lipin 1 (LPIN1) Proteine anzeigenProtein-Typ
Spezies
Quelle
Applikation
Reinheit
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Aufreinigungstag / Konjugat
- Dieses Lipin 1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
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Produktmerkmale
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- Recombinant human LPIN1 / Lipin-1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Kommentare
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The tag is located at the C-terminal.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Lagerung
- -80 °C
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Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Lipin 1 (LPIN1)
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Andere Bezeichnung
- Lpin1,lipin-1
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Hintergrund
- This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined.
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Molekulargewicht
- 98.5 kDa
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NCBI Accession
- NP_663731
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Pathways
- Monocarboxylic Acid Catabolic Process
Target
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