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LIN7C Protein (Myc-DYKDDDDK Tag)

LIN7C Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2724765
  • Target Alle LIN7C Produkte
    LIN7C (Lin-7 Homolog C (LIN7C))
    Protein-Typ
    Recombinant
    Spezies
    • 3
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 4
    • 2
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses LIN7C Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human LIN7C protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    LIN7C (Lin-7 Homolog C (LIN7C))
    Andere Bezeichnung
    Lin7c (LIN7C Produkte)
    Synonyme
    LIN7C Protein, fb75b09 Protein, wu:fb75b09 Protein, zgc:101881 Protein, LIN-7-C Protein, LIN-7C Protein, MALS-3 Protein, MALS3 Protein, VELI3 Protein, 9130007B12Rik Protein, AI303698 Protein, AU019331 Protein, AW125731 Protein, D2Ertd520e Protein, Veli3 Protein, lin-7 homolog C, crumbs cell polarity complex component Protein, lin-7 homolog C L homeolog Protein, lin-7 homolog C (C. elegans) Protein, LIN7C Protein, lin7c.L Protein, lin7c Protein, Lin7c Protein
    Hintergrund
    Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells. [UniProtKB/Swiss-Prot Function]
    Molekulargewicht
    21.7 kDa
    NCBI Accession
    NP_060832
    Pathways
    Synaptic Membrane
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