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ITGA8 Protein (Myc-DYKDDDDK Tag)

This anti-ITGA8 antibody (ABIN2723529) is a HEK-293 Cells antibody detecting ITGA8 in AbP, STD. Suitable for Human.
Produktnummer ABIN2723529

Kurzübersicht für ITGA8 Protein (Myc-DYKDDDDK Tag) (ABIN2723529)

Target

Alle ITGA8 Proteine anzeigen
ITGA8 (Integrin alpha-8 (ITGA8))

Protein-Typ

Recombinant

Spezies

Human

Quelle

  • 1
  • 1
HEK-293 Cells

Applikation

Antibody Production (AbP), Standard (STD)

Reinheit

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Aufreinigungstag / Konjugat

    Dieses ITGA8 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

    Produktmerkmale

    • Recombinant human Integrin alpha-8 / ITGA8 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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  • Applikationshinweise

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Lagerung

    -80 °C

    Informationen zur Lagerung

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    ITGA8 (Integrin alpha-8 (ITGA8))

    Andere Bezeichnung

    Integrin alpha-8,itga8

    Hintergrund

    Integrins are heterodimeric transmembrane receptor proteins that mediate numerous cellular processes including cell adhesion, cytoskeletal rearrangement, and activation of cell signaling pathways. Integrins are composed of alpha and beta subunits. This gene encodes the alpha 8 subunit of the heterodimeric integrin alpha8beta1 protein. The encoded protein is a single-pass type 1 membrane protein that contains multiple FG-GAP repeats. This repeat is predicted to fold into a beta propeller structure. This gene regulates the recruitment of mesenchymal cells into epithelial structures, mediates cell-cell interactions, and regulates neurite outgrowth of sensory and motor neurons. The integrin alpha8beta1 protein thus plays an important role in wound-healing and organogenesis. Mutations in this gene have been associated with renal hypodysplasia/aplasia-1 (RHDA1) and with several animal models of chronic kidney disease. Alternate splicing results in multiple transcript variants encoding distinct isoforms.

    Molekulargewicht

    117.3 kDa

    NCBI Accession

    NP_003629
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