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FIL1h Protein (Transcript Variant 2)

Dieses Recombinant FIL1h-Protein wird in Escherichia coli (E. coli) produziert.
Produktnummer ABIN2723382

Kurzübersicht für FIL1h Protein (Transcript Variant 2) (ABIN2723382)

Target

FIL1h (Interleukin 1 eta (FIL1h))

Protein-Typ

Recombinant

Biologische Aktivität

Active

Spezies

  • 8
  • 5
Human

Quelle

  • 11
  • 1
  • 1
Escherichia coli (E. coli)

Applikation

Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)

Reinheit

> 95 % as determined by SDS-PAGE and Coomassie blue staining
  • Proteineigenschaft

    Transcript Variant 2

    Spezifität

    Optimal preservation of protein structure, post-translational modifications and functions.

    Produktmerkmale

    • Recombinant human IL1F8 / IL1H2 (transcript variant 2) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.

    Endotoxin-Niveau

    Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).

    Biological Activity Comment

    Measured by its ability to induce IL-8 production by human PBMCs.
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  • Applikationshinweise

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2

    Handhabung

    Resuspend the protein in the desired concentration in proper buffer

    Lagerung

    -80 °C

    Informationen zur Lagerung

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    FIL1h (Interleukin 1 eta (FIL1h))

    Andere Bezeichnung

    Il1f8,il1h2

    Hintergrund

    The protein encoded by this gene is a member of the interleukin 1 cytokine family. Protein structure modeling indicated that this cytokine may contain a 12-stranded beta-trefoil structure that is conserved between IL1A (IL-A alpha) and IL1B (IL-1 beta). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.

    Molekulargewicht

    17.3 kDa

    NCBI Accession

    NP_775270
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