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FcRn Protein (Fc gamma Receptor and Transporter) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

FCGRT Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Pubmed (1 reference)
Produktnummer ABIN2720989
$1,019.70
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
20 μg
Lieferung in 11 Werktagen
  • Target Alle FcRn (FCGRT) Proteine anzeigen
    FcRn (FCGRT) (Fc gamma Receptor and Transporter (FCGRT))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    Transcript Variant 1
    Spezies
    • 12
    • 5
    • 5
    • 3
    • 3
    • 1
    Human
    Quelle
    • 15
    • 4
    • 3
    • 3
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses FcRn Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human FCGRT / FCRN (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Fan, Neubert: "Quantitative Analysis of Human Neonatal Fc Receptor (FcRn) Tissue Expression in Transgenic Mice by Online Peptide Immuno-Affinity LC-HRMS." in: Analytical chemistry, Vol. 88, Issue 8, pp. 4239-47, (2016) (PubMed).

  • Target
    FcRn (FCGRT) (Fc gamma Receptor and Transporter (FCGRT))
    Andere Bezeichnung
    Fcgrt,fcrn (FCGRT Produkte)
    Synonyme
    FCRN, alpha-chain, FcRn, Fc fragment of IgG receptor and transporter, Fc receptor, IgG, alpha chain transporter, FCGRT, Fcgrt
    Hintergrund
    This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants.
    Molekulargewicht
    39.6 kDa
    NCBI Accession
    NP_004098
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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