Fibrillarin Protein (FBL) (Myc-DYKDDDDK Tag)
Kurzübersicht für Fibrillarin Protein (FBL) (Myc-DYKDDDDK Tag) (ABIN2720913)
Target
Alle Fibrillarin (FBL) Proteine anzeigenProtein-Typ
Spezies
Quelle
Applikation
Reinheit
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Aufreinigungstag / Konjugat
- Dieses Fibrillarin Protein ist gelabelt mit Myc-DYKDDDDK Tag.
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Produktmerkmale
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- Recombinant human FBL protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Kommentare
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The tag is located at the C-terminal.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Lagerung
- -80 °C
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Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Fibrillarin (FBL)
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Andere Bezeichnung
- Fbl
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Hintergrund
- This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8 % of humans with the autoimmune disease scleroderma recognize fibrillarin.
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Molekulargewicht
- 33.6 kDa
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NCBI Accession
- NP_001427
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Pathways
- Ribonucleoside Biosynthetic Process
Target
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