Endothelin 1 Protein (EDN1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2720181

Produktdetails

Target: Endothelin 1 (EDN1)

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Endothelin 1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Endothelin-1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: Endothelin 1 (EDN1)

Andere Bezeichnung: Endothelin-1 (EDN1 Produkte)

Synonyme: et1 Protein, et-1 Protein, Edn1 Protein, EDN Protein, ET-1 Protein, ET1 Protein, PPET1 Protein, HDLCQ7 Protein, preproET Protein, Et1 Protein, fb14d01 Protein, wu:fb14d01 Protein, PPET-1 Protein, EDN1 Protein, edn1 Protein, edn1-a Protein, edn1-b Protein, endothelin 1 Protein, endothelin 1 S homeolog Protein, endothelin 1 L homeolog Protein, edn1 Protein, EDN1 Protein, Edn1 Protein, edn1.S Protein, edn1.L Protein

Hintergrund: This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 22.4 kDa

NCBI Accession: NP_001946

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size