Dystrophin Protein (DMD) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2719890

Produktdetails

Target: Dystrophin (DMD)

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Dystrophin Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Dystrophin / DMD (transcript variant Dp140b) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: Dystrophin (DMD)

Andere Bezeichnung: Dystrophin,dmd (DMD Produkte)

Synonyme: DMD Protein, Dmd Protein, MGC83347 Protein, DKFZp459C1629 Protein, dmd Protein, MGC79631 Protein, DKFZp468A1620 Protein, Dp71 Protein, cb664 Protein, zfDYS Protein, im:6911785 Protein, zgc:110165 Protein, BMD Protein, CMD3B Protein, DXS142 Protein, DXS164 Protein, DXS206 Protein, DXS230 Protein, DXS239 Protein, DXS268 Protein, DXS269 Protein, DXS270 Protein, DXS272 Protein, DXSmh7 Protein, DXSmh9 Protein, Dp427 Protein, dys Protein, mdx Protein, pke Protein, DNADMD1 Protein, RATDMD Protein, CG17750 Protein, CG31175 Protein, CG34157 Protein, CG7240 Protein, CG7243 Protein, CG7344 Protein, DLP Protein, DLP1 Protein, DLP186 Protein, DLP2 Protein, DLP3 Protein, DmDLP Protein, DmDYS Protein, Dmel\\CG34157 Protein, Dp117 Protein, Dp186 Protein, Dp205 Protein, GI3046716 Protein, IDLP Protein, det Protein, dmDLP Protein, dmDp186 Protein, dmDys Protein, dystrophin Protein, dystrophin, gene 1 L homeolog Protein, dystrophin, gene 1 Protein, dystrophin, muscular dystrophy Protein, Dystrophin Protein, DMD Protein, LOC708073 Protein, dmd.1.L Protein, LOC465557 Protein, dmd.1 Protein, dmd Protein, Dmd Protein, Dys Protein

Hintergrund: This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene.

Molekulargewicht: 143 kDa

NCBI Accession: NP_004012

Pathways: Skeletal Muscle Fiber Development